Ordering Recommendation

Mycoplasma pneumoniae Antibodies, IgG & IgM (0050399) is preferred.

Mnemonic

MYCO-G

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must  be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

< 0.10 U/L: Negative
0.10-0.32 U/L: Equivocal
> 0.32 U/L: Positive

Interpretive Data

Over 50 percent of healthy adults have a relatively high background of specific M. pneumoniae IgG antibodies in their sera, probably because of past M. pneumoniae infections. Therefore, paired sera obtained with a time interval of 1 to 3 weeks are highly recommended in adults to confirm reinfection by M. pneumoniae, which is demonstrated by a significant change in IgG antibodies. A significant change is indicated if one specimen is above 0.32 U/L and the other is below 0.20 U/L.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86738

Components

Component Test Code* Component Chart Name LOINC
0050397 Mycoplasma Pneumoniae Antibody IgG 5255-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • M pneumoniae antibody IgG
  • M pneumoniae IgG
Mycoplasma pneumoniae Antibody, IgG