Detect circulating immune complexes. Consider ordering Immune Complex Panel (0050667), which contains both Raji cell immune complex and C1q binding assays.
Quantitative Flow Cytometry
Plain red or serum separator tube (SST).
Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately. Transport 1 mL serum. (Min: 0.5 mL) If ordered in conjunction with a C1q Binding Assay, transfer TWO (2) 1 mL aliquots of serum to individual ARUP Standard Transport Tubes.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles.
Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 30 days
Many autoimmune disorders, chronic infections and malignancies are associated with circulating immune complexes. Quantitation of immune complexes assists in staging immunologic disorders.
Laboratory Developed Test (LDT)
Immune complexes bind to Raji Cells via their complement receptors. The immunoglobulin portion of the immune complex is then detected by flow cytometry with anti-human IgG-FITC.
|Component Test Code*||Component Chart Name||LOINC|
|0050302||Raji Cell Immune Complex Assay||10864-7|
- Immune Complex Assay