Ordering Recommendation

Not a stand-alone test. Order in conjunction with Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA (0050292).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) or plasma separator tube (PST).
Also acceptable: green (lithium heparin) or lavender (K2EDTA or K3EDTA).

Specimen Preparation

Allow serum tube to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 14 Days ; Frozen: 12 weeks (May have up to 5 freeze/thaw cycles.)

Methodology

Semi-Quantitative Electrochemiluminescent Immunoassay (ECLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  HSV 2 Glycoprotein G Antibody, IgG Less than or equal to 0.99 COI

Interpretive Data

  Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a nontype specific screening test.


HSV 2 Glycoprotein G Antibody, IgG
REFERENCE INTERVAL INTERPRETIVE COMMENT
0.99 COI or less Negative: No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
1.00 COI or greater Positive: IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.

Compliance Category

FDA

Note

For CSF specimens refer to Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050359).

Hotline History

N/A

CPT Codes

86696

Components

Component Test Code* Component Chart Name LOINC
0050294 HSV 2 Glycoprotein G Antibody, IgG 42338-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Herpes Simplex glycoprotein G
  • HerpeSelect
  • HSV-2
  • HSV 2 typing
  • HSV Type 2 IgG Specific Ab
  • HSV typing
Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA