Ordering Recommendation

Not a stand-alone test. Order in conjunction with Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA (0050292).

Mnemonic
HERP II
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Effective February 18, 2020
0.89 IV or less Negative - No significant level of detectable IgG antibody to HSV type 2 glycoprotein G.
0.90-1.09 IV Equivocal - Questionable presence of IgG antibody to HSV type 2 glycoprotein G.  Repeat testing in 10-14 days may be helpful.
1.10 IV or greater Positive - IgG antibody to HSV type 2 glycoprotein G detected, which may indicate a current or past HSV infection.

Interpretive Data

Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a non-type specific screening test.

Compliance Category

FDA

Note

For CSF specimens refer to Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050359).

Hotline History
N/A
CPT Codes

86696

Components
Component Test Code* Component Chart Name LOINC
0050294 HSV 2 Glycoprotein G Antibody, IgG 42338-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Herpes Simplex glycoprotein G
  • HerpeSelect
  • HSV 2 typing
  • HSV Type 2 IgG Specific Ab
  • HSV typing
  • HSV-2
Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA