0050292
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Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA

HERP I
Example Reports
Negative
Positive

Ordering Recommendation

Not a stand-alone test. Order in conjunction with Herpes Simplex Virus Type 2 Glycoprotein G-Specific Antibody, IgG by CIA (0050294). Because glycoprotein antibodies may require 3-6 months to form, follow-up testing is recommended to confirm a negative IgG glycoprotein result in the context of positive HSV Types 1 or 2 antibody results.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST) or plasma separator tube (PST). Also acceptable: green (lithium heparin) or lavender (K2EDTA or K3EDTA).

Specimen Preparation

Allow serum tube to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 14 days; Frozen: 12 weeks (May have up to 5 freeze/thaw cycles.)

Methodology

Semi-Quantitative Electrochemiluminescent Immunoassay (ECLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
 Components
 Reference Interval
  HSV 1 Glycoprotein G Ab, IgG Less than or equal 0.99 COI

Interpretive Data

  Individuals infected with HSV may not exhibit detectable IgG antibody to type-specific HSV antigens 1 and 2 in the early stages of infection. Detection of antibody presence in these cases may only be possible using a nontype specific screening test.


HSV 1 Glycoprotein G Ab, IgG
REFERENCE INTERVAL INTERPRETIVE COMMENT
0.99 COI or less Negative: No significant level of detectable IgG antibody to HSV type 1 glycoprotein G.
1.00 COI or greater Positive: IgG antibody to HSV type 1 glycoprotein G detected, which may indicate a current or past HSV infection

Compliance Category

FDA

Note

For CSF specimens, refer to Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by ELISA, CSF (ARUP test code 0050379).

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
04/20/2026
X
X
X
X
N/A

CPT Codes

86695

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Components

Component Test Code* Component Chart Name LOINC
0050292 HSV 1 Glycoprotein G Ab, IgG 42337-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • HerpeSelect
  • HSV-1
  • HSV 1
  • HSV Type 1 IgG Specific Ab
  • HSV Type 1 glycoprotein G
  • HSV typing 1
Herpes Simplex Virus Type 1 Glycoprotein G-Specific Antibody, IgG by CIA