Ordering Recommendation

Not recommended as a stand-alone test. Refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG with Reflex to Type 1 and 2 Glycoprotein G-Specific Ab, IgG (0051708).


Semi-Quantitative Chemiluminescent Immunoassay




Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Serum separator tube. Also acceptable: Serum from umbilical cord blood.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transport 1 mL serum. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature


Unacceptable Conditions

Urine. CSF (refer to Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG, CSF, ARUP test code 0050394). Contaminated, heat-inactivated, or hemolyzed specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
0.89 IV or less: Not Detected.
0.90-1.09 IV: Indeterminate - Repeat testing in 10-14 days may be helpful.
1.10 IV or greater: Detected.

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

No compliance statements are in use for this test.

Hotline History
Component Test Code* Component Chart Name LOINC
0050286 HSV Type 1/2 Combined Ab, IgG 27948-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Herpes Simplex Antibodies, IgG
  • Herpes Simplex Serology, Serum HSV 1,2
  • HSV 1 and 2
  • HSV 1, 2 IgG
  • HSV 1,2
Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgG