Ordering Recommendation

Not recommended as a stand-alone test. For initial establishment of diagnosis, refer to Coccidioides Antibodies Reflexive Panel (3001982).

Mnemonic
COCCI G
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
0.9 IV or less Negative - No significant level of Coccidioides IgG antibody detected.
1.0-1.4 IV Equivocal - Questionable presence of Coccidioides IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greater Positive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection.

Interpretive Data

IgG antibody usually appears by the third week of infection and may persist for years.  Both tube precipitin (TP) and CF antigens are represented in the ELISA tests.

Compliance Category

FDA

Note

Negative fungal serology does not rule out the possibility of current infection.

Hotline History
N/A
CPT Codes

86635

Components
Component Test Code* Component Chart Name LOINC
0050179 Coccidioides Antibody, IgG by ELISA 27009-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cocci IgG
  • Coccidioides IgG antibody
  • San Joaquin Fever antibodies
  • Valley fever antibodies
Coccidioides Antibody, IgG by ELISA