Coccidioides Antibodies, IgM by Immunoassay, Serum

0050178
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Example Reports
Negative
Positive

Ordering Recommendation

Use to screen for the presence of coccidioidal IgM antibodies in serum. Not recommended as a standalone test. For screening with confirmation, refer to Coccidioides Antibodies Reflexive Panel, Serum (3001982).

Mnemonic

COCCI M

Methodology

Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.

Remarks

Mark specimens plainly as "acute" or "convalescent."

Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

0.9 IV or less Negative - No significant level of Coccidioides IgM antibody detected.
1.0-1.4 IV Equivocal - Questionable presence of Coccidioides IgM antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greater Positive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection.

Interpretive Data

In most symptomatic patients, IgM antibody usually appears by the second week of infection and disappears by the fourth month. Both tube precipitin (TP) and CF antigens are represented in the ELISA tests.

Compliance Category

FDA

Note

This immunoassay uses recombinant and native Coccidioides antigens, including CF and TP antigens.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
05/18/2020
X
N/A

CPT Codes

86635

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Components

Component Test Code* Component Chart Name LOINC
0050178 Coccidioides Antibody, IgM by ELISA 90448-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • CF
  • Coccidioides immitis
  • Coccidioidomycosis
  • Precipitin
  • TP
  • Valley fever
Coccidioides Antibodies, IgM by Immunoassay, Serum