Use to screen for the presence of coccidioidal IgM antibodies in serum. Not recommended as a standalone test. For screening with confirmation, refer to Coccidioides Antibodies Reflexive Panel, Serum (3001982).
Enzyme-Linked Immunosorbent Assay (ELISA)
New York DOH Approval Status
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Other body fluids. Contaminated, hemolyzed, icteric, or lipemic specimens.
Mark specimens plainly as "acute" or "convalescent."
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|0.9 IV or less||Negative - No significant level of Coccidioides IgM antibody detected.|
|1.0-1.4 IV||Equivocal - Questionable presence of Coccidioides IgM antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.5 IV or greater||Positive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection.|
In most symptomatic patients, IgM antibody usually appears by the second week of infection and disappears by the fourth month. Both tube precipitin (TP) and CF antigens are represented in the ELISA tests.
This immunoassay uses recombinant and native Coccidioides antigens, including CF and TP antigens.
|Component Test Code*||Component Chart Name||LOINC|
|0050178||Coccidioides Antibody, IgM by ELISA||90448-2|
- Coccidioides immitis
- Valley fever