Histoplasma spp. Antibodies by Immunodiffusion

0050174
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Example Reports
Detected
None Detected

Ordering Recommendation

Not recommended as a stand-alone test. Refer to Histoplasma Antibodies by CF & ID (0050627).

Mnemonic

HISTO PPT

Methodology

Qualitative Immunodiffusion

Performed

Sun-Fri

Reported

3-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

None detected.

Interpretive Data

The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H). The M band often appears first and may occur without the H band. M precipitin is found in about 70 percent of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10 percent of patients.

Compliance Category

FDA

Note

Negative fungal serology does not rule out the possibility of current infection.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/17/2020
X
X
N/A

CPT Codes

86698

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Components

Component Test Code* Component Chart Name LOINC
0050174 Histoplasma spp. Abs, Precipitin 5218-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Histoplasma ID
  • Histoplasma Precipitin
  • Histoplasma spp Ab
  • Histoplasmosis Antibody
Histoplasma spp. Antibodies by Immunodiffusion