Ordering Recommendation

Not recommended as a stand-alone test. Refer to Histoplasma Antibodies by CF & ID (0050627).

Mnemonic
HISTO PPT
Methodology

Qualitative Immunodiffusion

Performed

Sun-Fri

Reported

3-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

None detected.

Interpretive Data

The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H). The M band often appears first and may occur without the H band. M precipitin is found in about 70 percent of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10 percent of patients.

Compliance Category

FDA

Note

Negative fungal serology does not rule out the possibility of current infection.

Hotline History
N/A
CPT Codes

86698

Components
Component Test Code* Component Chart Name LOINC
0050174 Histoplasma spp. Abs, Precipitin 5218-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Histoplasma ID
  • Histoplasma Precipitin
  • Histoplasma spp Ab
  • Histoplasmosis Antibody
Histoplasma spp. Antibodies by Immunodiffusion