Beta-2 Transferrin

0050047
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Example Reports
Abnormal
Normal
Ordering Recommendation

Aids in diagnosis of CSF leak.

Mnemonic
B2TRNSF
Methodology

Qualitative Immunofixation Electrophoresis

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Aural or nasal fluid in sterile container.

Specimen Preparation

Transport 2 mL aural or nasal fluid in a tube without preservative. (Min: 1 mL aural or nasal fluid)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 weeks

Reference Interval

None detected

Interpretive Data

Detection of a beta-2 transferrin band by IFE is diagnostic for the presence of cerebrospinal fluid (CSF). This test is useful in the differential diagnosis for CSF otorrhea or CSF rhinorrhea. Beta-2 transferrin is not detected by this methodology in normal serum, tears, saliva, sputum, nasal, or aural fluid.

The performance characteristics of this test were determined by ARUP Laboratories, Inc.

Compliance Category

Laboratory Developed Test (LDT)

Note

The beta-2 transferrin protein assay by IFE methodology is not a reliable method for detecting human perilymph due to the low sensitivity of the assay.

Hotline History
N/A
CPT Codes

86335

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Components
Component Test Code* Component Chart Name LOINC
0050047 Beta-2 Transferrin 13876-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cerebrospinal Fluid Leakage
  • Transferrin, Spinal Fluid
  • B2 Transferrin
  • CSF Leakage Detection
  • CSF Specific Transferrin
  • CSF-Specific Transferrin
  • Desialated Transferrin
  • Tau CSF Protein
  • Transferrin B2
Beta-2 Transferrin