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Glomerular Basement Membrane Antibody, IgG (IFA)
Copy Utility
Ordering Recommendation
May be useful in detecting glomerular basement membrane (GBM) antibodies. Combined use of IFA Glomerular Basement Membrane Antibody, IgG by Multiplex Bead Assay and IFA (2008403) may improve diagnostic sensitivity for disease. If positive, may be useful for monitoring treatment response.
Mnemonic
Methodology
Indirect Fluorescent Antibody
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transport 1 mL serum. (Min: 0.5 mL)
Refrigerated.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Negative
Interpretive Data
When present, IgG antibody to glomerular basement membrane (GBM) antigen detected by either indirect fluorescent antibody (IFA) or multiplex bead assay helps support a diagnosis of Goodpasture syndrome. However, the combined result of both assays performed during initial evaluation improves the diagnostic sensitivity for disease. A positive result in one or both assays should be confirmed by renal biopsy.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
86255
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0049191 | GBM Antibody, IgG by IFA | 29994-1 |
Aliases
- Anti-GBM Antibody
- Anti-Glomerular Basement Membrane Antibody
- GBM IgG IFA
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