Ordering Recommendation

Order to diagnose factor VIII deficiency, detect factor VIII inhibitors, and monitor factor VIII replacement therapy.

Mnemonic
F8 BETHR
Methodology

Electromagnetic Mechanical Clot Detection

Performed

Mon-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer two 3 mL aliquots of platelet-poor plasma to ARUP Standard Transport Tubes. (Min: 2 mL/each)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum. EDTA plasma, clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months

Reference Interval
Test Number
Components
Reference Interval
0030095 Factor VIII, Activity
Age Reference Interval
0-6 years 56-191%
7-9 years 76-199%
10-11 years 80-209%
12-13 years 72-198%
14-15 years 69-237%
16-17 years 63-221%
18 years and older 56-191%

Bethesda Quantitative, Factor VIII Effective May 19, 2014
0.5 BU or less

Interpretive Data



Compliance Category

Standard

Note

If Factor VIII activity is 20 percent or less, then Bethesda Quantitative, Factor VIII will be added.  Additional charges apply.

Hotline History
N/A
CPT Codes

85240; if reflexed, add 85335

Components
Component Test Code* Component Chart Name LOINC
0030028 Bethesda Quantitative, F8 3204-5
0030095 Factor VIII, Activity 3209-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Bethesda Quantitative Factor VIII, Inhibitor
  • Coagulation Factor VIII Inhibitor Panel, Plasma
  • Factor 8 Inhibitor
  • Factor VIII Inhibitor Profile
Factor VIII Activity with Reflex to Bethesda Quantitative, Factor VIII