Limited utility in determining manganese exposure. Manganese, Whole Blood (0099272) is recommended for determining recent, active exposure.
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician). High concentrations of iodine may interfere with elemental testing. Collection of urine specimens from patients receiving iodinated or gadolinium-based contrast media should be avoided for a minimum of 72 hours post-exposure. Collection from patients with impaired kidney function should be avoided for a minimum of 14 days post contrast media exposure.
24-hour or random urine collection. Specimen must be collected in a plastic container. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately, if tested within 14 days of collection.
Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL)
Refrigerated. Also acceptable: Room temperature or frozen.
Urine collected within 72 hours after administration of iodinated or gadolinium-based contrast media. Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element free transport tube (with the exception of the original device).
Record total volume and collection time interval on transport tube and on test request form.
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year
|Manganese, Urine - per volume||0.0-5.0 µg/L|
|Manganese, Urine - per 24h||0.0-5.0 µg/d|
|Manganese, Urine - ratio to CRT||0.0-5.0 µg/g CRT|
|Creatinine, Urine - per 24h||
This assay provides limited utility in determining manganese exposure. Whole blood measurements are recommended for determining recent or active exposure.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|0020207||Creatinine, Urine - per volume||2161-8|
|0020208||Creatinine, Urine - per 24h||2162-6|
|0025043||Manganese, Urine - ratio to CRT||29935-4|
|0025071||Manganese, Urine - per volume||21382-7|
|0025072||Manganese, Urine - per 24h||8203-2|
- Manganese/Creatinine, Random, Urine
- Mn Urine
- Mn/CRT ratio
- Normalized Urine Manganese
- random Mg Urine