Useful as a reasonable indicator of recent, active exposure and provides a modest indicator for distinguishing exposed from nonexposed individuals. Recommended for monitoring potential accumulation with TPN. Not recommended for detecting long-term, low-dose manganese exposure, refer to Manganese, RBC (2007254).
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).
Royal blue (K2EDTA or Na2EDTA).
Transport 7 mL whole blood in the original collection tube. (Min: 1 mL)
Room temperature. Also acceptable: Refrigerated.
Specimens collected in tubes other than Royal Blue (EDTA). Specimens transported in containers other than a Royal Blue (EDTA) tube or Trace Element-Free Transport Tube. Heparin anticoagulant. Clotted specimens.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Elevated results may be due to skin or collection-related contamination, including the use of a noncertified metal-free collection/transport tube. If contamination concerns exist due to elevated levels of blood manganese, confirmation with a second specimen collected in a certified metal-free tube is recommended.
Laboratory Developed Test (LDT)
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