Ordering Recommendation

Useful when exposure to arsenic is known but the species is uncertain. For initial testing, Arsenic, Urine with Reflex to Fractionated (0025000) is preferred.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately if tested within 14 days of collection.

Specimen Preparation

Transfer an 8 mL aliquot of urine from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 mL)

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Unacceptable Conditions

Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device).


Record total volume and collection time interval on transport tube and on test request form.


Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 months


Quantitative High Performance Liquid Chromatography (HPLC)/Quantitative Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)


Tue, Fri


1-10 days

Reference Interval

Test Number Components
Reference Interval
  Arsenic, Organic By report
  Arsenic, Inorganic By report
  Arsenic, Methylated By report

Interpretive Data

The ACGIH Biological Exposure Index for the sum of inorganic and methylated species of arsenic is 35 µg/L. Inorganic species of arsenic are most toxic. Methylated species arise primarily from metabolism of inorganic species but may also come from dietary sources and are of moderate toxic potential. The organic species of arsenic are considered nontoxic and arise primarily from food. The sum of the inorganic, methylated, and organic species of arsenic may be lower than the total arsenic concentration due to the presence of unidentified organic species of arsenic.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0020737 Arsenic, Inorganic 12481-8
0020740 Arsenic, Methylated 53779-5
0020741 Arsenic, Organic 53778-7
3016603 As Fractionation, Interpretation 93479-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • arsenic metabolites
  • arsenic, inorganic forms
  • arsenic, methylated forms
  • Arsenic, organic forms
  • As metabolites
  • As, inorganic forms
  • As, methylated forms
  • As, organic forms
  • ASFR
Arsenic, Fractionated, Urine