Ordering Recommendation

Use to assess cardiovascular disease risk and guide therapy.




Quantitative Spectrophotometry/Quantitative Enzymatic Assay




Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Patient must fast for 12-15 hours prior to collection.


Serum separator tube or plasma separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Body Fluid (refer to Cholesterol, Fluid, ARUP test code 0020714; Triglycerides, Fluid ARUP test code 0020713; and Chylomicron Screen, Body Fluid, ARUP test code 0098457).


After separation from cells: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 3 months

Reference Interval

By Report

Interpretive Data

An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor.  An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.

Non-HDL cholesterol is a secondary target of therapy in persons with high serum triglycerides (greater than 199 mg/dL).  The goal for non-HDL cholesterol in persons with high triglycerides is 30 mg/dL higher than their LDL cholesterol goal.

CHD Risk Factors
+1  Age: Men, 45 years and older
     Women, 55 years and older or premature menopause without estrogen therapy
+1 Family history of premature CHD
+1  Current smoking
+1  Hypertension
+1  Diabetes mellitus
+1  Low HDL cholesterol: 39 mg/dL or less
-1  High HDL cholesterol: 60 mg/dL or greater

20 years and older
Higher Risk
Total Cholesterol 199 mg/dL or less 200-239 mg/dL 240 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater 39 mg/dL or less
LDL Cholesterol 129 mg/dL or less
(99 mg/dL or less if patient has CHD)
130-159 mg/dL 160 mg/dL or greater
VLDL Cholesterol (calculated) 30 mg/dL or less

0-19 years
High Risk
Total Cholesterol 169 mg/dL or less 170-199 mg/dL 200 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater 39 mg/dL or less
LDL-Cholesterol (measured) 109 mg/dL or less 110-129 mg/dL 130 mg/dL or greater
VLDL Cholesterol (calculated) 30 mg/dL or less

Compliance Category



LDL-cholesterol is measured (not calculated) on this panel.

Hotline History


CPT Codes

80061; 83721


Component Test Code* Component Chart Name LOINC
0020031 Cholesterol, Serum or Plasma 2093-3
0020040 Triglycerides, Serum or Plasma 2571-8
0020053 HDL Cholesterol 2085-9
0020257 LDL Cholesterol, Direct 18262-6
0020550 VLDL, Calculated 13458-5
0020705 Non-HDL Cholesterol 43396-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Cholesterol, Serum or Plasma
  • Coronary Risk Panel
  • HDL Cholesterol
  • LDL Cholesterol, Direct
  • Lipid Panel
  • Non-HDL Cholesterol
  • Triglycerides, Serum or Plasma
  • VLDL, Calculated
Lipid Panel, Extended