Ordering Recommendation

Use to assess cardiovascular disease risk and guide therapy.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Patient must fast for 12-15 hours prior to collection.


Serum separator tube or plasma separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Body fluid (refer to Cholesterol, Fluid, ARUP test code 0020714; Triglycerides, Fluid ARUP test code 0020713; and Chylomicron Screen, Body Fluid, ARUP test code 0098457).


After separation from cells: Ambient: 8 hours; Refrigerated: 5 days; Frozen: 3 months


Quantitative Spectrophotometry/Quantitative Enzymatic Assay




Within 24 hours

Reference Interval

By Report

Interpretive Data

An HDL cholesterol less than 40 mg/dL is low and constitutes a coronary heart disease risk factor.  An HDL cholesterol greater than 60 mg/dL is a negative risk factor for coronary heart disease.

Non-HDL cholesterol is a secondary target of therapy in persons with high serum triglycerides (greater than 199 mg/dL).  The goal for non-HDL cholesterol in persons with high triglycerides is 30 mg/dL higher than their LDL cholesterol goal.

CHD Risk Factors
+1  Age: Men, 45 years and older
+1  Women, 55 years and older or premature menopause without estrogen therapy
+1  Family history of premature CHD
+1  Current smoking
+1  Hypertension
+1  Diabetes mellitus
+1  Low HDL cholesterol: 39 mg/dL or less
-1  High HDL cholesterol: 60 mg/dL or greater

20 years and older
Higher Risk
Total Cholesterol 199 mg/dL or less 200-239 mg/dL 240 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater 39 mg/dL or less
LDL Cholesterol 129 mg/dL or less
(99 mg/dL or less if patient has CHD)
130-159 mg/dL 160 mg/dL or greater
VLDL Cholesterol (calculated) 30 mg/dL or less

0-19 years
High Risk
Total Cholesterol 169 mg/dL or less 170-199 mg/dL 200 mg/dL or greater
Triglycerides 149 mg/dL or less 150-199 mg/dL 200-499 mg/dL
HDL Cholesterol 40 mg/dL or greater 39 mg/dL or less
LDL-Cholesterol (measured) 109 mg/dL or less 110-129 mg/dL 130 mg/dL or greater
VLDL Cholesterol (calculated) 30 mg/dL or less

Compliance Category



LDL-cholesterol is measured (not calculated) on this panel.

Hotline History


CPT Codes

80061; 83721


Component Test Code* Component Chart Name LOINC
0020031 Cholesterol, Serum or Plasma 2093-3
0020040 Triglycerides, Serum or Plasma 2571-8
0020053 HDL Cholesterol 2085-9
0020257 LDL Cholesterol, Direct 18262-6
0020550 VLDL, Calculated 13458-5
0020705 Non-HDL Cholesterol 43396-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Cholesterol, Serum or Plasma
  • Coronary Risk Panel
  • HDL Cholesterol
  • LDL Cholesterol, Direct
  • Lipid Panel
  • Non-HDL Cholesterol
  • Triglycerides, Serum or Plasma
  • VLDL, Calculated
Lipid Panel, Extended