Ordering Recommendation

Not the preferred test to evaluate for viral hepatitis. Preferred panel test to evaluate symptomatic patients for viral hepatitis is Hepatitis Panel, Acute with Reflex to HBsAg Confirmation and Reflex to HCV by Quantitative NAAT (3002989).




Qualitative Chemiluminescent Immunoassay




1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Refer to individual components.


Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL) Also acceptable: K2EDTA plasma.

Storage/Transport Temperature


Unacceptable Conditions

Heparinized plasma. Specimens containing particulate material. Heat inactivated, severely hemolyzed, or lipemic specimens.


After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Indefinitely (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Reference Interval
  Hepatitis A Antibody, IgM Negative
  Hepatitis B Core Antibody, IgM Negative
  Hepatitis B Surface Antigen Negative
  Hepatitis C Antibody by CIA Interp Negative

Interpretive Data

This panel of tests should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P

Compliance Category



Order this panel when the patient has had clinical acute hepatitis of unknown origin for less than six months. If results for HBsAg are repeatedly reactive with an index value between 1.00 and 50.00, then HBsAg Confirmation will be added. Additional charges apply.

Hotline History


CPT Codes

80074; if reflexed, add 87341


Component Test Code* Component Chart Name LOINC
0020089 Hepatitis B Surface Antigen 5196-1
0020092 Hepatitis B Core Antibody, IgM 24113-3
0020093 Hepatitis A Antibody, IgM 13950-1
0020099 Hepatitis C Antibody by CIA Interp 13955-0
0020179 Hepatitis, Acute Panel Interpretation 48767-8
2002404 Hepatitis C Antibody by CIA Index 57006-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Acute Hep Panel, reflex to confirmation
  • HAV IgM Ab
  • HBsAg confirmation
  • HBV core IgM Ab
  • HCV Ab
  • Hep Panel reflex to confirmation
  • Hepatitis A Antibody, IgM
  • Hepatitis B Core Antibody, IgM
  • Hepatitis B Surface Antigen
  • Hepatitis C Antibody
  • Hepatitis C Antibody by CIA
  • Hepatitis panel
  • Hepatitis screening panel
  • Hepatitis Screening Profile, Serum
  • Hepatitis, Acute Panel
  • Viral hepatitis panel
Hepatitis Panel, Acute with Reflex to HBsAg Confirmation (Change effective as of 11/14/22: Refer to 3002989)