Ordering Recommendation

Preferred panel to evaluate symptomatic patients for viral hepatitis. If acute HCV infection is suspected, the recommended test is Hepatitis C Virus (HCV) by Quantitative NAAT (3000572). This panel includes HAV IgM, HBV core antibody IgM, HBV surface antigen, and HCV antibody with reflex to HCV by quantitative NAAT.




Qualitative Chemiluminescent Immunoassay/Quantitative Transcription-Mediated Amplification




1-2 days
If reflexed, add 1-3 days.

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum separator tube (SST) or Pink (K2EDTA).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Standard Transport Tube. (Min: 2.0 mL) Also acceptable: K2EDTA plasma.

Storage/Transport Temperature


Unacceptable Conditions

Heparinized plasma. Specimens containing particulate material. Heat-inactivated, severely hemolyzed, or lipemic specimens.


After separation from cells: Ambient: Unacceptable; Refrigerated: 5 days; Frozen: 2 months (avoid freeze/thaw cycles)

Reference Interval

Test Number
Reference Interval
  Hepatitis B Surface Antigen Negative
  Hepatitis C Antibody by CIA Interp Negative
  Hepatitis B Core Antibody, IgM Negative
  Hepatitis A Antibody, IgM Negative

Interpretive Data

Component Interpretation
Hepatitis C Antibody by CIA Interp 0.79 IV or less   Negative
0.80 to 0.99 IV    Equivocal
1.00 to 10.99 IV  Low Positive
11.00 IV or greater   High Positive

Compliance Category



Order this panel when the patient has had clinical acute hepatitis of unknown origin for less than six months. If results for HBsAg are repeatedly reactive with an index value between 1.00 and 50.00, then HBsAg Confirmation will be added. If the anti-HCV antibody result is positive, then Hepatitis C Virus by Quantitative NAAT will be added. Additional charges apply.

Hotline History


CPT Codes

80074; if reflexed, add 87341, and 87522


Component Test Code* Component Chart Name LOINC
0020089 Hepatitis B Surface Antigen 5196-1
0020092 Hepatitis B Core Antibody, IgM 24113-3
0020093 Hepatitis A Antibody, IgM 13950-1
2002404 Hepatitis C Antibody by CIA Index 57006-9
3003010 Hepatitis, Acute Panel w/ Rflx Interp 48767-8
3003128 Hepatitis C Antibody by CIA Interp 13955-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Acute Hep Panel, reflex to confirmation
  • HAV IgM Ab
  • HBsAg confirmation
  • HBV core IgM Ab; HCV Ab
  • Hep Panel reflex to confirmation
  • Hepatitis A Antibody, IgM
  • Hepatitis B Core Antibody, IgM
  • Hepatitis B Surface Antigen
  • Hepatitis C Antibody
  • Hepatitis C Antibody by CIA
  • Hepatitis panel
  • Hepatitis screening panel
  • Hepatitis Screening Profile, Serum
  • Hepatitis, Acute Panel
  • Viral hepatitis panel
Hepatitis Panel, Acute with Reflex to HBsAg Confirmation and Reflex to HCV by Quantitative NAAT