Hepatitis Panel, Acute with Reflex to HBsAg Confirmation and Reflex to HCV by Quantitative NAAT
Ordering Recommendation
Preferred panel to evaluate symptomatic patients for viral hepatitis. If acute HCV infection is suspected, the recommended test is Hepatitis C Virus (HCV) by Quantitative NAAT (3000572). This panel includes HAV IgM, HBV core antibody IgM, HBV surface antigen, and HCV antibody with reflex to HCV by quantitative NAAT.
New York DOH Approval Status
Specimen Required
Serum separator tube (SST), lavender (EDTA) or pink (K2EDTA).
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.0 mL serum or plasma to an ARUP standard transport tube (Min: 2.5 mL). This test requires a dedicated transport tube submitted only for HEPACUTEQR testing.
Frozen.
Heparinized plasma. Specimens containing particulate material. Heat-inactivated, severely hemolyzed, or lipemic specimens.
After separation from cells: Ambient: 12 hours; Refrigerated: 6 days; Frozen: 2 months (avoid freeze/thaw cycles)
Methodology
Qualitative Chemiluminescent Immunoassay (CLIA)/Quantitative Polymerase Chain Reaction (PCR)
Performed
Sun-Sat
Reported
1-2 days
If reflexed, add 1-3 days.
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Hepatitis B Surface Antigen | Negative | |
Hepatitis C Antibody by CIA Interp | Negative | |
Hepatitis B Core Antibody, IgM | Negative | |
Hepatitis A Antibody, IgM | Negative |
Interpretive Data
Component |
Interpretation |
---|---|
Hepatitis C Antibody by CIA Interp | 0.79 IV or less: Negative 0.80 to 0.99 IV: Equivocal 1.00 to 10.99 IV: Low Positive 11.00 IV or greater: High Positive |
FDA
Note
Order this panel when the patient has had clinical acute hepatitis of unknown origin for less than six months. If results for HBsAg are repeatedly reactive with an index value between 1.00 and 50.00, then HBsAg Confirmation will be added. If the anti-HCV antibody result is positive, then Hepatitis C Virus (HCV) by Quantitative NAAT will be added. Additional charges apply.
Hotline History
Hotline History
CPT Codes
80074; if reflexed, add 87341, and 87522
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0020089 | Hepatitis B Surface Antigen | 5196-1 |
0020092 | Hepatitis B Core Antibody, IgM | 24113-3 |
0020093 | Hepatitis A Antibody, IgM | 13950-1 |
2002404 | Hepatitis C Antibody by CIA Index | 57006-9 |
3003010 | Hepatitis, Acute Panel w/ Rflx Interp | 48767-8 |
3003128 | Hepatitis C Antibody by CIA Interp | 13955-0 |
Aliases
- Acute Hep Panel, reflex to confirmation
- HAV IgM Ab
- HBsAg confirmation
- HBV core IgM Ab; HCV Ab
- Hep Panel reflex to confirmation
- Hepatitis A Antibody, IgM
- Hepatitis B Core Antibody, IgM
- Hepatitis B Surface Antigen
- Hepatitis C Antibody
- Hepatitis C Antibody by CIA
- Hepatitis panel
- Hepatitis screening panel
- Hepatitis Screening Profile, Serum
- Hepatitis, Acute Panel
- Viral hepatitis panel