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Coccidioides Antibody Reflexive Panel
3001982
Ordering Recommendation

Preferred serology test to detect coccidioidomycosis (Valley fever).

Mnemonic
COCCI R
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay, Semi-Quantitative Complement Fixation, Qualitative Immunodiffusion
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
Serum Separator Tube (SST). 
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic specimens. 
Remarks
Please mark specimens plainly as "acute" or "convalescent." 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Components
Reference Interval
0050179Coccidioides Antibody, IgG by ELISA
0.9 IV or lessNegative - No significant level of Coccidioides IgG antibody detected.
1.0-1.4 IVEquivocal - Questionable presence of Coccidioides IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greaterPositive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection.

0050178Coccidioides Antibody, IgM by ELISA
0.9 IV or lessNegative - No significant level of Coccidioides IgM antibody detected.
1.0-1.4 IVEquivocal - Questionable presence of Coccidioides IgM antibody detected.  Repeat testing in 10-14 days may be helpful.
1.5 IV or greaterPositive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection.

0050183Coccidioides immitis Antibodies by ImmunodiffusionNone detected.
 Coccidioide Titer, Complement FixationLess than 1:2

Interpretive Data
Refer to report.

Note
Negative fungal serology does not rule out the possibility of current infection. Coccidioides Antibody IgG and IgM by ELISA are used to screen for Coccidioides antibodies. If the ELISA testing is equivocal or positive for IgG and/or IgM, then Coccidioides immitis Angibodies by Immunodiffusion, and Coccidioide Titer will be added. Additional charges apply.
Hotline History
View Hotline History
CPT Code(s)
86635 x2; if reflexed add 86635 x2
Components
Component Test Code*Component Chart NameLOINC
0050178Coccidioides Antibody, IgM by ELISA90448-2
0050179Coccidioides Antibody, IgG by ELISA27009-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases