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Coccidioides Antibodies, IgG and IgM by ELISA, CSF
3000057
Ordering Recommendation

Aid in diagnosis of coccidioidal meningitis (Valley fever). Preferred test is Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.

Mnemonic
COCCIGMCSF
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
 
Collect
CSF. 
Specimen Preparation
Transfer 2 mL CSF to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Refrigerated. 
Unacceptable Conditions
Contaminated, hemolyzed, xanthochromic, or severely lipemic specimens. 
Remarks
Please Mark specimens plainly as "acute" or "convalescent." 
Stability
Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles) 
Reference Interval
Test Number
Components
Reference Interval
3000055Coccidioides Antibody IgG ELISA, CSF
0.9 IV or lessNegative - No significant level of Coccidioides IgG antibody detected.
1.0-1.4 IVEquivocal - Questionable presence of Coccidioides IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.5 IV or greaterPositive - Presence of IgG antibody to Coccidioides detected, suggestive of current or past infection.

3000056Coccidioides Antibody IgM ELISA, CSF
0.9 IV or lessNegative - No significant level of Coccidioides IgM antibody detected.
1.0-1.4 IVEquivocal - Questionable presence of Coccidioides IgM antibody detected. Repeat testing in 10-14 days may be helpful.
1.5 IV or greaterPositive - Presence of IgM antibody to Coccidioides detected, suggestive of current or recent infection.


Interpretive Data
Refer to report.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Negative fungal serology does not rule out the possibility of current infection.
Hotline History
View Hotline History
Components
Component Test Code*Component Chart NameLOINC
3000062Coccidioides Antibody IgG ELISA, CSF16638-9
3000063Coccidioides Antibody IgM ELISA, CSF16639-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cocci Abs ELISA
  • Cocci IgG, IgM Abs