Risperidone and Metabolite, Serum or Plasma
2007951
Ordering Recommendation
Therapeutic monitoring of risperidone (eg, Risperdal).
Mnemonic
RISPERIDON
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun, Wed
Reported
1-5 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Pre-dose (trough) draw - At steady state concentration.  
Collect
Lavender (EDTA), pink (K2EDTA) or plain red.  
Specimen Preparation
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).  
Remarks
N/A  
Stability
Ambient: 2 weeks; Refrigerated: 2 weeks; Frozen: 2 months  
Reference Interval
 
 
Therapeutic range Not well established
Total (Risperidone and Metabolite) 20-​60 ng/mL
Toxic range Not well established
Interpretive Data
Adverse effects to risperidone therapy may include headache, nausea, dizziness, tachycardia, orthostatic hypotension and dyskinesia.

See Compliance Statement B: www.aruplab.com/CS  
Note
 
CPT Code(s)
80299
Components
Component Test Code*Component Chart Name
2007952Risperidone Serum/Plasma
20079539 OH Risperidone Serum/Plasma
2007954Total Risper/9 OH Risper
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 9-Hydroxyrisperidone
  • risperdal blood level
  • Risperdal®
  • risperidone blood level