Ethyl Glucuronide Screen with Reflex to Confirmation, Urine
Ordering Recommendation

Useful for general screening in the assessment of ethanol exposure in the contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out ethanol exposure. For follow-up testing of a presumptive result, Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative (2007909) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Random urine. 
Specimen Preparation
Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days 
Reference Interval
Screen cutoff concentration: 500 ng/mL
Interpretive Data
Ethyl glucuronide is a direct metabolite of ethanol and can be detected up to 80 hours in urine after ethanol ingestion. The cutoff for positive by immunoassay is set at 500 ng/mL. A positive result will be confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS).

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
CPT Code(s)
80307; if reflexed, add 80321 (Reflexed Alt Code: G0480 )
Component Test Code*Component Chart NameLOINC
2007913Ethyl Glucuronide Screen w/Rflx, Urine58375-7
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