Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative
Ordering Recommendation

May be useful in the assessment of ethanol exposure in the contexts of compliance and/or abuse. For general screening, Ethyl Glucuronide Screen with Reflex to Quantitation, Urine (2007912) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Mon, Wed, Sat
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Random urine.  
Specimen Preparation
Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)  
Storage/Transport Temperature
Unacceptable Conditions
Ambient: 20 days; Refrigerated: 20 days; Frozen: 20 days  
Reference Interval
Interpretive Data
Ethyl glucuronide (EtG) and Ethyl Sulfate (EtS) are direct metabolites of ethanol. EtG and EtS can be detected up to 80 hours in urine after ethanol ingestion and the presence of both metabolites can be used as markers for recent alcohol use. The presence of EtG, alone in urine, is not a unique marker of ethanol ingestion. False positive EtG results can occur from microbial formation or from fermentation and false negative EtG results can occur from bacterial degradation. The analytical measurement range is 100-10,000 ng/mL.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
CPT Code(s)
80321 (Alt code: G0480)
Component Test Code*Component Chart NameLOINC
2007910Ethyl Glucuronide, Urn, Quant58378-1
2007911Ethyl Sulfate, Urn, Quant58425-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.