Ordering Recommendation

Intended for use in patients with viral loads ≥500 copies/mL. HIV-1 combined pheno- and genotyping test to provide antiretroviral susceptibility information for protease inhibitors (PI) and reverse transcriptase inhibitors (ie, NRTI and NNRTI). Preferred test for patients with known or suspected complex drug resistance patterns (eg, suboptimal virologic response to treatment and viral load rebound).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or plasma preparation tube (PPT).

Specimen Preparation

Separate from cells within 6 hours of collection. Transfer 3 mL plasma to an ARUP standard transport tube and freeze immediately. (Min: 1 mL)
Test is not performed at ARUP; separate specimens must be submitted when multiple tests are ordered.

Storage/Transport Temperature

CRITICAL FROZEN.

Unacceptable Conditions

Thawed specimens.

Remarks

Provide patient's most recent viral load and viral load collection date.

Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Methodology

Polymerase Chain Reaction (PCR)/Culture/Sequencing

Performed

Varies

Reported

27-38 days

Reference Interval

By report

Interpretive Data



Compliance Category

Performed by non-ARUP Laboratory

Note

Procedure should be used for patients with documented HIV-1 infection and viral loads greater than 500 copies/mL.

Hotline History

N/A

CPT Codes

87900; 87901; 87903; 87904 x12

Components

Component Test Code* Component Chart Name LOINC
0092073 Viral Load 59419-2
0092074 Viral Load Date 45353-0
2003232 EER HIV PhenoSense GT 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • HIV Resistance
HIV PhenoSense GT

Monogram Biosciences