Vitamin B1 (Thiamine), Plasma
0080389
Ordering Recommendation
Do not use to determine thiamine deficiency.
Mnemonic
VIT B1 P
Methodology
Quantitative High Performance Liquid Chromatography
Performed
Sun-Sat
Reported
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Green (sodium or lithium heparin), lavender (EDTA), plasma separator tube, or pink (K2 EDTA).  
Specimen Preparation
Separate plasma from cells within one hour of collection. Protect from light within one hour of collection, and during storage and transport. Transfer 3 mL plasma to an ARUP Amber Transport Tube. (Min: 0.2 mL)  
Storage/Transport Temperature
Frozen. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Hemolyzed specimens or specimens other than heparin or EDTA plasma.  
Remarks
  
Stability
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen at -20°C: 6 months  
Reference Interval
8-30 nmol/L  
Interpretive Data
Total thiamine, measured as thiamine (vitamin B1) and thiamine monophosphate, is reported. However, thiamine diphosphate (TDP), the biologically active form of the vitamin, is best measured in whole blood and is not found in measurable concentration in plasma. Plasma thiamine concentration reflects recent intake rather than body stores.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
Whole blood is the preferred specimen for thiamine assessment. Approximately 80 percent of thiamine present in whole blood is found in red blood cells. Refer to Vitamin B1 (Thiamine), Whole Blood (0080388).
CPT Code(s)
84425
Components
Component Test Code*Component Chart Name
0080389Vitamin B1, Plasma
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Aliases
  • B1 Vitamin
  • Thiamine
  • Thiamine monophosphate
  • Vitamin B1 (Thiamine),
  • VITB1