Vitamin B1 (Thiamine), Whole Blood
Ordering Recommendation
Use for nutritional assessment of vitamin B1 (thiamine).
Methodology
Quantitative High Performance Liquid Chromatography (HPLC)/Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
2-4 days
New York DOH Approval Status
Specimen Required
Green (Sodium or Lithium Heparin), Lavender (EDTA), or Pink (K2EDTA).
Transfer 3 mL whole blood to an ARUP Standard Transport Tube. (Min: 0.6 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Any specimen other than whole blood. Plasma separator tubes. Glass tubes. Clotted or non-frozen specimens.
Ambient: Unacceptable; Refrigerated: 4 hours; Frozen: 6 months
Reference Interval
70-180 nmol/L
Interpretive Data
This assay measures the concentration of thiamine diphosphate (TDP), the primary active form of vitamin B1. Approximately 90 percent of vitamin B1 present in whole blood is TDP. Thiamine and thiamine monophosphate, which comprise the remaining 10 percent, are not measured.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Whole blood is the preferred specimen for thiamine assessment. Approximately 80 percent of thiamine present in whole blood is found in red blood cells.
Hotline History
CPT Codes
84425
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0080388 | Vitamin B1, Whole Blood | 74444-1 |
Aliases
- B1 Vitamin
- TDP
- Thiamine
- Thiamine Diphosphate
- Thiamine Pyrophosphate
- TPP
- VITB1