Cytomegalovirus Antibody, IgM
0050553
Ordering Recommendation
Not recommended as a standalone test. If using serology testing, IgM combined with IgG is preferred. Do not use for diagnosis in immunocompromised individuals. Preferred test for detecting CMV infection is quantitative PCR (0051813).
Submit With Order
Mnemonic
CMV IGM
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube. Also acceptable: Serum from umbilical cord blood.  
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Acute and convalescent specimens must be labeled as such; parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or urine. Contaminated, heat-inactivated or hemolyzed specimens.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
29.9 AU/mL or less: Not Detected.
30.0-​34.9 AU/mL: Indeterminate -​ Repeat testing in 10-​14 days may be helpful.
35.0 AU/mL or greater: Detected -​ IgM antibody to CMV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-​infection.
Interpretive Data
CMV serology is not useful for the evaluation of active or reactivated infection in immunocompromised patients. Molecular diagnostic tests (i.e., PCR) are preferred in these cases.
Note
This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
CPT Code(s)
86645
Components
Component Test Code*Component Chart Name
0050553CMV Antibody IgM
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • CMV
  • CMV Antibody
  • CMV IgM