Ordering Recommendation
Aid in discriminating between current and past cytomegalovirus infection in immunocompetent individuals.
Mnemonic
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Plasma or urine. Contaminated, hemolyzed, or heat-inactivated specimens.
Label specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
CMV Antibody IgM | 29.9 AU/mL or less |
Interpretive Data
Component | Interpretation |
---|---|
Cytomegalovirus Antibody, IgG | 0.59 U/mL or less: Not Detected. 0.60-0.69 U/mL: Indeterminate - Repeat testing in 10-14 days may be helpful. 0.70 U/mL or greater: Detected. |
Cytomegalovirus Antibody, IgM | 29.9 AU/mL or less: Not Detected. 30.0-34.9 AU/mL: Indeterminate - Repeat testing in 10-14 days may be helpful. 35.0 AU/mL or greater: Detected - IgM antibody to CMV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
FDA
Note
This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).
Hotline History
CPT Codes
86644; 86645
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050165 | CMV Antibody IgG | 5124-3 |
0050553 | CMV Antibody IgM | 7853-5 |
Aliases
- CMV Antibodies
- CMV IgG & IgM
- Cytomegalovirus (CMV) Antibodies, IgG and IgM, Serum