Beta-2 Glycoprotein 1 Antibodies, IgG & IgM
0050321
Ordering Recommendation
Acceptable initial test for strong suspicion of antiphospholipid syndrome (APS). Order with lupus anticoagulant (LA) (0030181) and anticardiolipin (aCL) IgG and IgM (0099344) assays.
Mnemonic
B2GPI PAN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Plasma or other body fluids. Contaminated, hemolyzed, grossly icteric, or severely lipemic specimens.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
 
 
Test Number Components Reference Interval
 Beta-​2 Glycoprotein 1 Antibody, IgG 0-​20 SGU
 Beta-​2 Glycoprotein 1 Antibody, IgM 0-​20 SMU
Interpretive Data
An IgG and/or IgM result of greater than 20 SGU and/or SMU on at least two occasions and at least 12 weeks apart is suggestive of antiphospholipid syndrome. Diagnosis should NOT be made solely on the basis of a single specimen.  
Note
 
CPT Code(s)
86146 x2
Components
Component Test Code*Component Chart Name
0050322B2Glycoprotein 1, IgG Antibody
0050323B2Glycoprotein 1, IgM Antibody
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ?2-glycoprotein 1 antibodies
  • Anti-B2-Glycoprotein 1
  • Anti-B2-Glycoprotein I (Beta-2 Glycoprotein 1 Antibodies, IgG & IgM)
  • Anti-B2-GP 1
  • Anti-B2-GP1
  • Anti-B2-GPI
  • Anti-beta-2 glycoprotein 1
  • Anti-Beta-2-Glycoprotein I
  • Apolipoprotein H
  • Apolipoprotein H, APOH
  • B2GP Antibodies
  • B2GP1
  • B2GPI IgG, IgM, IgA
  • BECKY
  • Beta 2 GP1 Ab IgA
  • Beta 2 GP1 Ab IgG
  • Beta 2 GP1 Ab IgM
  • Beta 2GP1 Ab
  • Beta-2 Glycoprotein 1