Histoplasma spp. Antibodies by Immunodiffusion
0050174
Ordering Recommendation
 
Mnemonic
HISTO PPT
Methodology
Qualitative Immunodiffusion
Performed
Sun-Fri
Reported
2-4 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
  
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min 0.1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Body fluids.  
Remarks
  
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
None detected.  
Interpretive Data
The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H). The M band often appears first and may occur without the H band. M precipitin is found in about 70 percent of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10 percent of patients.  
Note
Negative fungal serology does not rule out the possibility of current infection.
CPT Code(s)
86698
Components
Component Test Code*Component Chart Name
0050174Histoplasma spp. Abs, Precipitin
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Histoplasma ID
  • Histoplasma Precipitin
  • Histoplasma spp Ab