Histoplasma spp. Antibodies by Immunodiffusion
0050174
 
Ordering Recommendation
Mnemonic
HISTO PPT
Methodology
Qualitative Immunodiffusion
Performed
Sun-Fri
Reported
2-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
 
Collect
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min 0.1 mL)  
Storage/Transport Temperature
Refrigerated.  
Unacceptable Conditions
Body fluids.  
Remarks
 
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)  
Reference Interval
None detected.
Interpretive Data
The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H). The M band often appears first and may occur without the H band. M precipitin is found in about 70 percent of both acute and chronic histoplasmosis cases. Both M and H occur together in only about 10 percent of patients.
Note
Negative fungal serology does not rule out the possibility of current infection.
CPT Code(s)
86698
Components
Component Test Code*Component Chart Name
0050174Histoplasma spp. Abs, Precipitin
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, contact interface support at interface.support@aruplab.com.
Cross References
  • Histoplasma ID
  • Histoplasma Precipitin
  • Histoplasma spp Ab