Rapid Plasma Reagin (RPR) with Reflex to Titer, FTA-ABS and TP-PA
Ordering Recommendation
Not an optimal reflex test. Preferred test is RPR with Reflex to TP-PA (0050478).
Submit With Order
Semi-Quantitative Charcoal Agglutination/Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Particle Agglutination
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Serum separator tube.  
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)  
Storage/Transport Temperature
Unacceptable Conditions
CSF or plasma. Contaminated, hemolyzed, or severely lipemic specimens.  
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year  
Reference Interval
Test Number Components Reference Interval
Rapid Plasma Reagin (RPR) Effective May 21, 2012
RPR (+) = Reactive
RPR (-​) = Nonreactive
Rapid Plasma Reagin (RPR) Titer < 1:1
0050477Treponema pallidum Antibody (FTA-​ABS), Serum, IgG by IFA with Reflex to Treponema pallidum Antibody by TP-​PA
Test Code Components Reference Interval
T.Pallidum Ab, IgG (FTA-​ABS) Nonreactive
0050777 Treponema pallidum Antibody by TP-​PA Nonreactive
0050777Treponema pallidum Antibody by TP-​PA Nonreactive
Interpretive Data
This panel is for clients in states where automatic confirmation using a treponemal test is required for all reactive RPR tests.

If RPR is reactive, then a titer to endpoint and FTA-ABS confirmation will be added. If FTA-ABS is inconclusive, TP-PA will be added. Additional charges apply.
CPT Code(s)
86592; if reflexed, add 86593; 86780; if reflexed, add 86780
Component Test Code*Component Chart Name
0050472Rapid Plasma Reagin (RPR)
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Cross References
  • Rapid Plasma Reagin (RPR) with Reflex to Treponema Antibody Confirmation
  • RPR Reflex to Titer, FTA-ABS and TPPA