Ordering Recommendation

Recommended test for syphilis screening and diagnosis (traditional algorithm).

Methodology

Semi-Quantitative Particle Agglutination

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Avoid freezing if possible.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, CSF, or other body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Components
Reference Interval
  Rapid Plasma Reagin (RPR) Non Reactive
  Rapid Plasma Reagin (RPR) Titer < 1:1
  Treponema pallidum Ab by TP-PA Reflex Nonreactive

Interpretive Data



Compliance Category

FDA

Note

This panel is for clients in states where automatic confirmation using a treponemal test is required for all reactive RPR tests.

If RPR is reactive, then a titer to endpoint and TP-PA confirmation will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86592; if reflexed, add 86593; 86780

Components

Component Test Code* Component Chart Name LOINC
0050472 Rapid Plasma Reagin (RPR) 20507-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Rapid Plasma Reagin (RPR) with MHA-TP Confirmation
  • RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing
  • RPR Reflex Titer & TPPA
  • RPR Reflex TPPA & Titer
  • RPR Reflex with confirmation
  • Treponema pallidum with Reflex to Titer and TP-PA Confirmation
Rapid Plasma Reagin (RPR) with Reflex to Titer and TP-PA Confirmation