Ordering Recommendation

Recommended test for syphilis screening and diagnosis (traditional algorithm).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Avoid freezing if possible.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, grossly hemolyzed, grossly lipemic, plasma, CSF, or other body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Particle Agglutination

Performed

Sun-Sat

Reported

1-4 days

Reference Interval

Test Number
Components
Reference Interval
  Rapid Plasma Reagin (RPR) Non Reactive
  Rapid Plasma Reagin (RPR) Titer < 1:1
  Treponema pallidum Ab by TP-PA Reflex Nonreactive

Interpretive Data



Compliance Category

FDA

Note

This panel is for clients in states where automatic confirmation using a treponemal test is required for all reactive RPR tests.

If RPR is reactive, then a titer to endpoint and TP-PA confirmation will be added. Additional charges apply.

Hotline History

N/A

CPT Codes

86592; if reflexed, add 86593; 86780

Components

Component Test Code* Component Chart Name LOINC
0050472 Rapid Plasma Reagin (RPR) 20507-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Rapid Plasma Reagin (RPR) with MHA-TP Confirmation
  • RPR (Diagnosis) with Reflex to Titer and Confirmatory Testing
  • RPR Reflex Titer & TPPA
  • RPR Reflex TPPA & Titer
  • RPR Reflex with confirmation
  • Treponema pallidum with Reflex to Titer and TP-PA Confirmation
Rapid Plasma Reagin (RPR) with Reflex to Titer and TP-PA Confirmation