von Willebrand Multimeric Panel
Ordering Recommendation
Not recommended for initial screening except in suspected cases of acquired von Willebrand disease (vWD) or high suspicion of vWD. Preferred initial test is von Willebrand Panel with Reflex to von Willebrand Multimeric Analysis (2003387).
Electrophoresis/Western Blot/Clotting/Microlatex Particle-Mediated Immunoassay/Platelet Agglutination
1-11 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Lt. blue (sodium citrate). Refer to Specimen Handling at for hemostasis/thrombosis specimen handling guidelines.  
Specimen Preparation
Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)  
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.  
Unacceptable Conditions
Serum, EDTA plasma, clotted or hemolyzed specimens.  
Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months  
Reference Interval
Test Number Components Reference Interval
 von Willebrand Multimeric  Normal
0030095Factor VIII, Activity 0-​6 years: 56-​191%
7-​9 years: 76-​199%
10-​11 years: 80-​209%
12-​13 years: 72-​198%
14-​15 years: 69-​237%
16-​17 years: 63-​221%
18 years and older: 56-​191%
0030285von Willebrand Factor Antigen 0-​6 years: 52-​214%
7-​9 years: 62-​180%
10-​11 years: 63-​189%
12-​13 years: 60-​189%
14-​15 years: 57-​199%
16-​17 years: 50-​205%
18 years and older: 52-​214%
0030250von Willebrand Factor Activity (Ristocetin Cofactor) 0-​6 years: 51-​215%
7-​9 years: 52-​176%
10-​11 years: 60-​195%
12-​13 years: 50-​184%
14-​15 years: 50-​203 %
16-​17 years: 49-​204%
18 years and older: 51-​215%
Interpretive Data
CPT Code(s)
85247; 85240; 85246; 85245
Component Test Code*Component Chart NameLOINC
0030003von Willebrand Multimeric32217-2
0030095Factor VIII, Activity3209-4
0030250von Willebrand Factor, Activity (RCF)6014-5
0030285von Willebrand Factor, Antigen27816-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Factor VIII
  • Factor VIII, Activity
  • RCF
  • Ristocetin Cofactor
  • von Willebrand Factor, Activity
  • von Willebrand Factor, Antigen
  • von Willebrand Multimeric
  • vW Activity
  • vW multimeric
  • vWAg
  • VWF:A
  • VWF:Rco