Arsenic, Fractionated, Urine
Ordering Recommendation

Useful when exposure to arsenic is known but the species is uncertain. For initial testing, Arsenic, Urine with Reflex to Fractionated (0025000) is preferred.

Quantitative High Performance Liquid Chromatography/Quantitative Inductively Coupled Plasma-Mass Spectrometry
Sun, Tue, Thu, Sat
1-10 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
24-hour or random urine collection. Specimen must be collected in a plastic container and should be refrigerated during collection. ARUP studies indicate that refrigeration of urine alone, during and after collection, preserves specimens adequately if tested within 14 days of collection. 
Specimen Preparation
Transfer an 8 mL aliquot of urine from a well-mixed collection to ARUP Trace Element-Free Transport Tubes (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 2 mL) 
Storage/Transport Temperature
Refrigerated. Also acceptable: Room temperature or frozen. 
Unacceptable Conditions
Urine collected within 48 hours after administration of a gadolinium (Gd) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device). 
Record total volume and collection time interval on transport tube and on test request form. 
Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 year 
Reference Interval
Test NumberComponents
Reference Interval
 Arsenic, OrganicBy report
 Arsenic, InorganicBy report
 Arsenic, MethylatedBy report

Interpretive Data
The ACGIH Biological Exposure Index for the sum of inorganic and methylated species of arsenic is 35 µg/L. Inorganic species of arsenic are most toxic. Methylated species arise primarily from metabolism of inorganic species but may also come from dietary sources and are of moderate toxic potential. The organic species of arsenic are considered nontoxic and arise primarily from food. The sum of the inorganic, methylated, and organic species of arsenic may be lower than the total arsenic concentration due to the presence of unidentified organic species of arsenic.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0020737Arsenic, Inorganic12481-8
0020740Arsenic, Methylated53779-5
0020741Arsenic, Organic53778-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • arsenic metabolites
  • arsenic, inorganic forms
  • arsenic, methylated forms
  • Arsenic, organic forms
  • As metabolites
  • As, inorganic forms
  • As, methylated forms
  • As, organic forms
  • ASFR