Zinc, Serum or Plasma
0020097
Ordering Recommendation
May be useful as an indicator of acute deficiency. For acute toxicity, Zinc, Urine (0020462) may be a more reliable indicator of exposure.
Mnemonic
ZINC
Methodology
Quantitative Inductively Coupled Plasma-Mass Spectrometry
Performed
Sun-Sat
Reported
1-2 days  
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
Specimen Required
Patient Preparation
Diet, medication, and nutritional supplements may introduce interfering substances. Upon the advice of their physician, patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications for one week prior to sample draw.  
Collect
Royal blue (no additives), or royal blue (EDTA).  
Specimen Preparation
Do not allow serum or plasma to remain on cells. Centrifuge and pour off serum or plasma ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)  
Storage/Transport Temperature
Room temperature. Also acceptable: Refrigerated or frozen.  
Unacceptable Conditions
Separator tubes. Specimens that are not separated from the red cells or clot. Hemolyzed specimens.  
Remarks
  
Stability
If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.  
Reference Interval
60-120 µg/dL  
Interpretive Data
Circulating zinc concentrations are dependent on albumin status and are depressed with malnutrition. Zinc may also be lowered with infection, inflammation, stress, oral contraceptives, and pregnancy. Zinc may be elevated with zinc supplementation or fasting. Elevated zinc concentrations may interfere with copper absorption.

See Compliance Statement B: www.aruplab.com/CS
Statement B: This test was developed and its performance characteristics determined by ARUP Laboratories. The U.S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
 
Note
Elevated results from noncertified trace element-free tubes may be due to contamination.  Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).
CPT Code(s)
84630
Components
Component Test Code*Component Chart Name
0020097Zinc, Serum/Plasma
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • serum zinc level
  • Zn
  • ZNS