May be useful as an indicator of acute deficiency. For acute toxicity, Zinc, Urine (0020462
) may be a more reliable indicator of exposure.
Quantitative Inductively Coupled Plasma-Mass Spectrometry
This test is New York DOH approved.
- Patient Preparation
- Diet, medication, and nutritional supplements may introduce interfering substances. Upon the advice of their physician, patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, and nonessential over-the-counter medications for one week prior to sample draw.
- Royal blue (no additives), or royal blue (EDTA).
- Specimen Preparation
- Do not allow serum or plasma to remain on cells. Centrifuge and pour off serum or plasma ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Trace Element-Free Transport Tube (ARUP supply #43116). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
- Storage/Transport Temperature
- Room temperature. Also acceptable: Refrigerated or frozen.
- Unacceptable Conditions
- Separator tubes. Specimens that are not separated from the red cells or clot. Hemolyzed specimens.
- If the specimen is drawn and stored in the appropriate container, the trace element values do not change with time.
Circulating zinc concentrations are dependent on albumin status and are depressed with malnutrition. Zinc may also be lowered with infection, inflammation, stress, oral contraceptives, and pregnancy. Zinc may be elevated with zinc supplementation or fasting. Elevated zinc concentrations may interfere with copper absorption.
Elevated results from noncertified trace element-free tubes may be due to contamination. Elevated concentrations of trace elements in serum should be confirmed with a second specimen collected in a trace element-free tube, such as royal blue sterile tube (no additive).
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