Ordering Recommendation

Useful for general screening in the assessment of ethanol exposure in the contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out ethanol exposure. For follow-up testing of a presumptive result, Ethyl Glucuronide and Ethyl Sulfate, Urine, Quantitative (2007909) is preferred. Results do not accurately correlate with amount or frequency of ethanol use.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Random urine.

Specimen Preparation

Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month

Methodology

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

Reference Interval

Screen cutoff concentration: 500 ng/mL

Interpretive Data

Ethyl glucuronide is a direct metabolite of ethanol and can be detected up to 80 hours in urine after ethanol ingestion. The cutoff for positive by immunoassay is set at 500 ng/mL. A positive result will be confirmed by liquid chromatography tandem mass spectrometry (LC-MS/MS).

Compliance Category

FDA

Note

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test code 2007909) will be added to confirm result. Additional charges apply.

Hotline History

N/A

CPT Codes

80307; if reflexed, add 80321 (Reflexed Alt Code: G0480 )

Components

Component Test Code* Component Chart Name LOINC
2007913 Ethyl Glucuronide Screen w/Rflx, Urine 58375-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Ethyl Glucuronide Screen with Reflex to Confirmation, Urine