Iodine, Urine
Ordering Recommendation

Recommended for the assessment of iodine nutritional status. This test reports total iodine from all iodine-containing species present in the specimen but does not determine the chemical form (species) of the iodine present. For determination of iodine excess and monitoring iodine overload in patients administered iodine-containing medications, refer to Iodine, Serum (2007463).

Quantitative Inductively Coupled Plasma-Mass Spectrometry
Tues, Thu, Sat
1-5 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Diet, medication, and nutritional supplements may introduce interfering substances. Patients should be encouraged to discontinue nutritional supplements, vitamins, minerals, nonessential over-the-counter medications for 48 hours (upon the advice of their physician). In addition, the administration of iodine-based contrast media and drugs containing Iodine may yield elevated results. Specimen must be collected in a plastic container and should be refrigerated after collection. 
24-hour or random urine collection. 
Specimen Preparation
Transfer an 8 mL aliquot from a well-mixed collection to ARUP Trace Element-Free Tubes (ARUP supply #43116) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 1 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Specimens not received in Trace Element-Free tubes. Urine collected within 48 hours after administration of a gadolinium (Gd) or iodine (I) containing contrast media (may occur with MRI studies). Acid preserved urine. Specimens contaminated with blood or fecal material. Specimens transported in non-trace element-free transport tube (with the exception of the original device). 
Record the total volume and collection time interval on transport tube and on test request form. 
Ambient: 2 months; Refrigerated: 2 months; Frozen: 2 months 
Reference Interval
Test Number
Reference Interval
 Iodine, Urine - per volume
16 years and older26.0-705.0 ug/L

 Iodine, Urine - per 24h
16 years and older93.0 - 1125.0 ug/d

Iodine per gram of CreatinineNo reference interval (µg/g crt)
0020473Creatinine, Urine - per 24h
3-8 years140-700 mg/d140-700 mg/d
9-12 years300-1300 mg/d300-1300 mg/d
13-17 years500-2300 mg/d400-1600 mg/d
18-50 years1000-2500 mg/d700-1600 mg/d
51-80 years800-2100 mg/d500-1400 mg/d
81 years and older600-2000 mg/d400-1300 mg/d

Interpretive Data
Values greater than 1000 µg/L may indicate dietary excess, but more frequently suggest recent drug or contrast media exposure.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
Component Test Code*Component Chart NameLOINC
0020207Creatinine, Urine - per volume2161-8
0020208Creatinine, Urine - per 24h2162-6
0097110Total Volume19153-6
0097111Hours Collected30211-7
2007466Iodine, Urine - per volume26842-5
2007467Iodine, Urine - per 24h2492-7
2007468Iodine, per gram of CRT55928-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • I urine
  • Iodide urine
  • Urinary Free Iodine
  • Urinary Iodine