Oxycodone/Oxymorphone, Urine Screen with Reflex to Quantitation
Ordering Recommendation

Useful for general screening in contexts of compliance and/or abuse. A screen with reflex testing is the preferred method for ruling out opiate exposure. For follow-up testing of a presumptive result, Opiates, Urine, Quantitative (0090364) is preferred.

Qualitative Enzyme Immunoassay/Quantitative Liquid Chromatography-Tandem Mass Spectrometry
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Random urine. 
Specimen Preparation
Transfer 4 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 2 mL) 
Storage/Transport Temperature
Unacceptable Conditions
Specimens exposed to repeated freeze/thaw cycles. 
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years 
Reference Interval
Effective May 16, 2011

Screen cutoff concentration: 100 ng/mL
Interpretive Data
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies. Specimens for which drugs or drug classes are detected by the screen are reflexed to a second, more-specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

This test detects oxycodone and oxymorphone. The confirmation test detects and quantifies morphine, codeine, hydrocodone, hydromorphone, 6-monoacetylmorphine, oxycodone and oxymorphone.

If the specimen screens positive, then Confirmation/Quantitation by LC-MS/MS (ARUP test 0090364) will be added to confirm result. Additional charges apply.

For detection of morphine, hydrocodone, and similar compounds, see Opiates Screen with Reflex to Confirmation, Urine (ARUP test code 2005093).
Hotline History
View Hotline History
CPT Code(s)
80307; if reflexed, add 80361; 80365 (Reflexed Alt Code: G0480 )
Component Test Code*Component Chart NameLOINC
2005102Oxycodone/Oxymorphone, Urn, Screen58430-0
2012212Screen, Urine Interpretation54247-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Oxycodone, w/ Confirmation w/ medMATCH, Urine