Tramadol and Metabolite, Urine, Quantitative
Ordering Recommendation
Preferred test to follow-up presumptive results. For general screening, Tramadol, Urine Screen with Reflex to Quantitation (2012297) is preferred.
New York DOH Approval Status
Specimen Required
Random urine.
Transfer 2 mL urine with no additives or preservatives an ARUP Standard Transport Tube. (Min: 1 mL)
Room temperature.
Specimens exposed to repeated freeze/thaw cycles.
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-6 days
Reference Interval
Effective May 2018
Drugs Covered | Cutoff Concentrations |
Tramadol | 25 ng/mL |
O-desmethyltramadol | 25 ng/mL |
Interpretive Data
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Positive cutoff:
Tramadol: 25 ng/mL
O-desmethyltramadol: 25 ng/mL
For medical purposes only; not valid for forensic use.
The presence of metabolite(s) without parent drug is common and may indicate use of parent drug during the prior week.
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
80373 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2002740 | O-desmethyltramadol, Urn, Quant | 92639-4 |
2002769 | Tramadol, Urn, Quant | 17719-6 |
Aliases
- O-Desmethyltramadol
- Ryzolt
- Tramadol, Quantitative, Urine
- Tramal
- Ultracet
- Ultram
- urine tramadol concentration
- urine ultram concentration