Methadone and Metabolite, Urine, Quantitative
Ordering Recommendation
Use to obtain quantitative results or to follow up a presumptive result. For general screening, the preferred test is Methadone Urine Screen with Reflex to Quantitation (2012245).
New York DOH Approval Status
Specimen Required
Random urine.
Transfer 1 mL with no additives or preservatives urine to an ARUP standard transport tube. (Min: 0.5 mL)
Room temperature.
Specimens exposed to repeated freeze/thaw cycles.
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Sun-Sat
Reported
1-7 days
Reference Interval
Drugs Covered | Cutoff Concentrations |
Methadone | 100 ng/mL |
EDDP | 100 ng/mL |
Interpretive Data
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Positive cutoff: 100 ng/mL
For medical purposes only; not valid for forensic use.
The absence of expected drug(s) and/or drug metabolite(s) may indicate noncompliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
Laboratory Developed Test (LDT)
Note
Compare to Pain Management, Methadone, Quantitative, with medMATCH, Urine; Pain Management, Methadone, with Confirmation with medMATCH, Urine.
Hotline History
Hotline History
CPT Codes
80358 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2005890 | Methadone, Urn, Quant | 3774-7 |
2005891 | EDDP, Urn, Quant | 50542-0 |
Aliases
- Amidone
- Dolophine
- EDDP
- Heptadon
- Methadone
- Methadose
- Pain Management
- Physeptone
- Symoron