Cytomegalovirus Antibody, IgM
Ordering Recommendation

Not recommended as a standalone test. If using serology testing, IgM combined with IgG is preferred. Do not use for diagnosis in immunocompromised individuals. Preferred test for detecting CMV infection is Cytomegalovirus by Quantitative PCR (0051813).

Semi-Quantitative Chemiluminescent Immunoassay
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Submit With Order
ARUP Consult®
Disease Topics
Specimen Required
Patient Preparation
Serum Separator Tube (SST). 
Specimen Preparation
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. 
Storage/Transport Temperature
Unacceptable Conditions
Contaminated, heat-inactivated or grossly hemolyzed specimens. 
Label specimens plainly as acute or convalescent. 
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles) 
Reference Interval
29.9 AU/mL or less:Not Detected.
30.0-34.9 AU/mL:Indeterminate - Repeat testing in 10-14 days may be helpful.
35.0 AU/mL or greater:Detected - IgM antibody to CMV detected, which may indicate a current or recent infection.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data
CMV serology is not useful for the evaluation of active or reactivated infection in immunocompromised patients. Molecular diagnostic tests (i.e., PCR) are preferred in these cases.

This test should not be used for blood donor screening, associated re-entry protocols, or for screening Human Cell, Tissues and Cellular and Tissue-Based Products (HCT/P).

Hotline History
View Hotline History
Component Test Code*Component Chart NameLOINC
0050553CMV Antibody IgM7853-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • CMV
  • CMV Antibody
  • CMV IgM