Chimerism, Posttransplant
Ordering Recommendation
Use to monitor chimerism and engraftment in recipients of allogeneic hematopoietic stem cell transplant. Aids in evaluating the relative amounts of recipient and donor cells present post transplant. Each posttransplant specimen and test ordered must have a unique ARUP accession number.
New York DOH Approval Status
Specimen Required
Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B). OR bone marrow in lavender (EDTA).
Transport 2 mL whole blood (Min: 1 mL) OR 1 mL bone marrow (Min: 1 mL).
Refrigerated. Also acceptable: Ambient.
Posttransplant results will be compared to pretransplant recipient and donor genotypes, therefore, donor and recipient specimens must be obtained and genotyped before the transplant event occurs.
If cell sorting is required, refer to:
Chimerism, Posttransplant, Sorted Cells (T Cells) (3005393) or
Chimerism, Posttransplant, Sorted Cells (B Cells) (3005401) or
Chimerism, Posttransplant, Sorted Cells (CD33+ Cells) (3005409) or
Chimerism, Posttransplant, Sorted Cells (Granulocytes) (3005417) or
Chimerism, Posttransplant, Sorted Cells (Monocytes) (3005425) or
Chimerism, Posttransplant, Sorted Cells (CD34+ Cells) (3005433) or
Chimerism, Posttransplant, Sorted Cells (56+ Cells) (3005441)
Room temperature: 1 week; Refrigerated: 1 month; Frozen: Unacceptable
Methodology
Polymerase Chain Reaction (PCR)/Fragment Analysis
Performed
Sun-Sat
Reported
5-10 days
Reference Interval
Interpretive Data
Refer to report
Laboratory Developed Test (LDT)
Note
Type Donor: Donor cells only.
Type Recipient: Recipient cells only.
Mixed: Donor and recipient cells present. Semiquantitative results of percentage of donor and recipient cells will be reported.
Hotline History
CPT Codes
81267
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3005455 | Chimerism Post, Specimen | |
3005456 | Chimerism Post, InformativeLoc | |
3005457 | Chimerism Post, Percent Recip | |
3005458 | Chimerism Post, Percent Donor | |
3005459 | Chimerism Post, Margin Error | |
3005460 | Chimerism Post, Interpretation |
Aliases
- Bone marrow DNA typing
- Bone Marrow DNA Typing Transplant Eval., Post-Transplant
- Bone Marrow Post-Trans Eval
- Bone Marrow Transplantation
- Chimerism Evaluation
- Transplant Analysis
- Transplant Evaluation