3004310
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CYP2B6

2B6GENO
Example Reports
Negative
Positive

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Informed Consent for Genetic Testing (Required for NY patients)

Ordering Recommendation

Use to assess genetic risk of abnormal drug metabolism for CYP2B6 substrates. May aid in drug selection and dose planning for drugs metabolized by CYP2B6.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), pink (K2EDTA), or yellow (ACD solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or serum. Specimens collected in sodium heparin or lithium heparin. Frozen specimens in glass collection tubes.

Remarks
Stability

Ambient: 72 hours; Refrigerated: 1 week; Frozen: 1 month

Methodology

Polymerase Chain Reaction (PCR)/Fluorescence Monitoring

Performed

Varies

Reported

5-10 days

Reference Interval

By report

Interpretive Data

Refer to report.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

Whole blood is the preferred specimen. Saliva samples that yield inadequate DNA quality and/or quantity will be reported as inconclusive if test performance does not meet laboratory-determined criteria for reporting.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/13/2023
X
05/15/2023
X
N/A

CPT Codes

81479

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Components

Component Test Code* Component Chart Name LOINC
3004492 2B6 Specimen 66746-9
3004493 CYP2B6 Genotype 72882-4
3004494 CYP2B6 Phenotype 79720-9
3004495 2B6 Interpretation 77202-0
3016891 EER CYP2B6 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • 2B6
  • bupropion
  • CYP2B6
  • Cytochrome P450 2B6
  • efavirenz
  • methadone
  • nevirapine
CYP2B6