Ordering Recommendation

Identify individuals at increased risk for statin-related muscle toxicity.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or pink (K2EDTA), or yellow (ACD Solution A or B).

Specimen Preparation

Transport 3 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Preferred transport temp: Refrigerated.

Unacceptable Conditions

Plasma or serum. Heparinized specimens. Frozen specimens in glass collection tubes.

Remarks

Counseling and informed consent are recommended for genetic testing. Consent forms are linked above.
New York Clients: informed consent is required with submission.

Stability

Room temperature: 3 days; Refrigerated: 1 week; Frozen: 1 month

Methodology

Polymerase Chain Reaction (PCR) / Fluorescence Monitoring

Performed

Mon, Thu

Reported

5-10 days

Reference Interval

Refer to report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

81328

Components

Component Test Code* Component Chart Name LOINC
2008427 SLCO1B1, 1 Variant, Specimen 66746-9
2008428 SLCO1B1, 1 Variant,*5 Genotype 93412-5
3016893 EER SLCO1B1 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Simvastatin myotoxicity assay
  • Statin-induced myopathy assay
SLCO1B1, 1 Variant