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Chromosome Analysis, Bone Marrow with Reflex to Genomic Microarray

BM REFLEX
Example Reports
Abnormal
Normal

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Time Sensitive

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Oncology Test Request Form Recommended (ARUP form #43099)

Ordering Recommendation

Use for diagnosis, prognosis, and monitoring of hematopoietic neoplasms. Microarray performed when karyotype results are reported as "normal" or "no growth."

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation
Collect

Nondiluted bone marrow aspirate. Collect in a heparinized syringe.

Specimen Preparation

Do not freeze or expose to extreme temperatures. Transfer 3 mL bone marrow to a green (sodium heparin) tube. (Min: 0.5 mL)

Storage/Transport Temperature

Room temperature

Unacceptable Conditions

Clotted specimens

Remarks

Clinical indication or reason for testing and specimen type required with test order. Sample will still be processed if this information is not initially provided but appropriate culturing and reporting may be compromised or delayed.
Indicate if patient has received a bone marrow transplant and specify sex of donor.

Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Methodology

Giemsa Band / Genomic Microarray (Oligo-SNP Array)

Performed

Sun-Sat

Reported

3-9 days
If reflexed, add 7-12 days.

Reference Interval

Refer to report

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

These studies involve culturing of living cells; therefore, turnaround times given represent average times, which are subject to multiple variables.

A processing fee will be charged if this procedure is canceled at the client's request after the test has been set up or if the specimen integrity is inadequate to allow culture growth.

If Chromosome Analysis is "normal" or "no growth," then Genomic Microarray testing will be added. Additional charges apply.

Specimens enrolled in external studies (e.g. COG studies) requireing additional work-up and/or supplementary data collection and submission will have the following charges added based on type and extent of work performed: Cytogenetics Study Submission - Basic (3006071) or Cytogenetics Study Submission - Extensive (3006072).

Hotline History

N/A

CPT Codes

88237; 88264; if reflexed, add 81277; for COG studies, add 88299

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0097605 Chromosome Analysis, Bone Marrow 50659-2
2009470 EER Chrom Analysis BM w/Rflx to Array
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Bone marrow karyotype
  • Cytogenomic SNP Microarray - Oncology
  • genomic microarray
Chromosome Analysis, Bone Marrow with Reflex to Genomic Microarray