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Acute Lymphoblastic Leukemia (ALL) Panel by FISH, Adult
Ordering Recommendation
Recommended FISH panel for adults with newly diagnosed ALL.
New York DOH Approval Status
Specimen Required
Nondiluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Whole blood in green (sodium heparin) tube.
Bone Marrow: Transfer 3 mL bone marrow to a green (sodium heparin). (Min: 1 mL)
Whole Blood: Transport 5 mL whole blood. (Min: 2 mL)
Room temperature.
Paraffin-embedded specimens. Clotted specimens.
Clinical indication or reason for testing and specimen type required with test order. Sample will still be processed if this information is not initially provided but appropriate culturing and reporting may be compromised or delayed.
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Methodology
Fluorescence in situ Hybridization (FISH)
Performed
Sun-Sat
Reported
3-9 days
Reference Interval
Refer to report
Interpretive Data
Probes included: BCR/ABL, MLL, E2A, IGH, MYC
Analyte Specific Reagent (ASR)
Note
A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the sample integrity is inadequate to allow culture growth. To order probes separately, refer to Chromosome FISH, Interphase (2002298).
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
If cell pellets or dropped cytogenetics slides are not submitted, a processing fee will apply.
This test must be ordered using Oncology test request form #43099 or through ARUP interface.
If chromosome analysis is not performed at ARUP on the same sample, Bone Marrow/PBL Culture Processing Fee (0093271) will be added to account for sample processing, and additional charge will apply. If multiple FISH tests are ordered, 0093271 will only be applied to one of the FISH tests.
Hotline History
CPT Codes
88271 x5; 88275 x5
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2002648 | ALL Panel by FISH, Adult | 57802-1 |
| 2002649 | EER ALL Panel by FISH, Adult | 11526-1 |
