3021360
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MALT1 (18q21) Gene Rearrangement by FISH

MALT1 FISH

Ordering Recommendation

Use to detect MALT1 rearrangements to aid in the diagnosis and prognostication in mucosa-associated lymphoid tissue (MALT Lymphoma).

New York DOH Approval Status

This test is not New York state approved.

Specimen Required

Patient Preparation
Collect

Tumor tissue.

Specimen Preparation

Formalin fix (10 percent neutral buffered formalin) and paraffin embed tumor tissue. Protect paraffin block and/or slides from excessive heat. Transport tissue block or 4 unstained, consecutively cut, 4-micron thick sections, mounted on positively charged glass slides in a tissue transport kit (ARUP supply #47808 recommended but not required) available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at 800-522-2787. (Min: 3 slides)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives (alcohol, Prefer) or heavy metal fixatives (B-4 or B-5). No tumor in tissue. Decalcified specimens.

Remarks

Include surgical pathology report.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Methodology

Qualitative Fluorescence in situ Hybridization (FISH)

Performed

Mon-Fri

Reported

3-7 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
11/03/2026
X
N/A

CPT Codes

88366

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Components

Component Test Code* Component Chart Name LOINC
3000703 Scoring Method 81304-8
3021361 MALT1 FISH Reference Number 94736-6
3021362 MALT1 FISH Source 31208-2
3021363 MALT1 FISH Result 66950-7
3021365 Total Cell Count 78236-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

MALT1 (18q21) Gene Rearrangement by FISH