Ordering Recommendation

Test is used to measure the concentration of plasma factor-H, a complement regulatory protein. The target patient population may include individuals undergoing workup for atypical hemolytic uremic syndrome (aHUS), complement 3 glomerulopathy (C3G), and age-related macular degeneration (AMD), among other diseases.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Pink (K2EDTA), tan (K2EDTA), royal blue (K2EDTA), or lavendar (EDTA).

Specimen Preparation

Separate plasma from cells within 2 hours of collection. Transfer plasma (minimum 0.5 mL) to an ARUP standard transport tube and freeze immediately.

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Nonfrozen specimens. Specimens exposed to repeated freeze/thaw cycles. Grossly hemolyzed, lipemic, and icteric specimens. Serum samples. Heparinized and lithium plasma samples.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 30 days

Methodology

Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Tue

Reported

2-12 days

Reference Interval

Test Number
Components
Reference Interval
  Complement Factor-H Conc, Plasma 156-325 ug/mL

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86160

Components

Component Test Code* Component Chart Name LOINC
3020710 Complement Factor-H Conc, Plasma 4519-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Complement Factor H
  • Factor H
Complement Factor-H Concentration, Plasma