3020347
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Prosthetic Joint Infection Panel by PCR

PJIPCR

Ordering Recommendation

Aid in the diagnosis of specific agents of joint infection. Results should be used in conjunction with other clinical and laboratory findings. This panel is not intended to monitor treatment for joint infections.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

N/A

Collect

Synovial Fluid (SF)

Specimen Preparation

Transfer 0.5 mL synovial fluid to a sterile ARUP standard transport tube (ARUP supply #43115) available online through eSupply using ARUP Connect or contact ARUP Client Services at 800-522-2787. (Min: 0.25 mL) Do not centrifuge.

Storage/Transport Temperature

Refrigerated or frozen

Unacceptable Conditions

Specimens that have been pre-processed or placed into transport media or treated with anticoagulants before testing.

Remarks
Stability

Ambient: 8 hours
Refrigerated: 7 days
Frozen: 7 days

Methodology

Qualitative Polymerase Chain Reaction (PCR)

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Interpretive Data

Negative results may be due to infection with pathogens that are not detected by this test, pathogens present below the limit of detection of the assay, or infection that may not be detected in a synovial fluid specimen. Positive results do not rule out co-infection with other organisms.

Compliance Category

FDA

Note

This assay detects Anaerococcus prevotii/vaginalis, Finegoldia magna, Streptococcus spp., Clostridium perfringens, Parvimonas micra, Streptococcus agalactiae, Cutibacterium avidum/granulosum, Peptoniphilus, Streptococcus pneumoniae, Enterococcus faecalis, Peptostreptococcus anaerobius, Streptococcus pyogenes, Enterococcus faecium, Staphylococcus aureus, Staphylococcus lugdunensis, Bacteroides fragilis, Kingella kingae, Proteus spp., Citrobacter, Klebsiella aerogenes, Pseudomonas aeruginosa, Enterobacter cloacae complex, Klebsiella pneumoniae group, Salmonella spp., Escherichia coli, Morganella morganii, Serratia marcescens, Haemophilus influenzae, Neisseria gonorrhoeae, Candida spp., and Candida albicans.
This panel contains assays for the detection of genetic determinants associated with S. aureus resistance to methicillin (mecA/C in conjunction with the SCCmec right extremity junction (MREJ)), enterococcal resistance to vancomycin (vanA and vanB) and some mechanisms of gram-negative bacterial resistance to beta-lactams including penicillins, cephalosporins, monobactams, and carbapenems (blaCTX-M, blaIMP, blaKPC, blaNDM, blaOXA-48-like, blaVIM). Negative results for these select antimicrobial resistance gene assays do not indicate susceptibility, as multiple mechanisms of resistance to methicillin, vancomycin, and beta-lactams exist.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
01/26/2026
X
N/A

CPT Codes

87999

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Components

Component Test Code* Component Chart Name LOINC
3020346 Anaerococcus prevotii/vaginalis by PCR 97609-2
3020348 Clostridium perfringens by PCR 97614-2
3020349 Cutibacterium avidum/granulosum by PCR 97615-9
3020350 Enterococcus faecalis by PCR 97617-5
3020351 Enterococcus faecium by PCR 97618-3
3020352 Finegoldia magna by PCR 97620-9
3020353 Parvimonas micra by PCR 97627-4
3020354 Peptoniphilus by PCR 97628-2
3020355 Peptostreptococcus anaerobius by PCR 97629-0
3020356 Staphylococcus aureus by PCR 97634-0
3020357 Staphylococcus lugdunensis by PCR 97635-7
3020358 Streptococcus spp. by PCR 97639-9
3020359 Streptococcus agalactiae by PCR 97636-5
3020360 Streptococcus pneumoniae by PCR 97637-3
3020361 Streptococcus pyogenes by PCR 97638-1
3020362 Bacteroides fragilis by PCR 97610-0
3020363 Citrobacter by PCR 97613-4
3020364 Enterobacter cloacae complex by PCR 97616-7
3020365 Escherichia coli by PCR 97619-1
3020366 Haemophilus influenzae by PCR 97621-7
3020367 Kingella kingae by PCR 97622-5
3020368 Klebsiella aerogenes by PCR 97623-3
3020369 Klebsiella pneumoniae group by PCR 97624-1
3020370 Morganella morganii by PCR 97625-8
3020371 Neisseria gonorrhoeae by PCR 97626-6
3020372 Proteus spp. by PCR 97630-8
3020373 Pseudomonas aeruginosa by PCR 97631-6
3020374 Salmonella spp. by PCR 97632-4
3020375 Serratia marcescens by PCR 97633-2
3020376 Candida spp. by PCR 97612-6
3020377 Candida albicans by PCR 97611-8
3020497 mecA/C and MREJ (MRSA) by PCR 96309-0
3020498 CTX-M by PCR 88250-6
3020499 VIM by PCR 85501-5
3020500 OXA-48-like by PCR 85827-4
3020501 KPC by PCR 49617-4
3020502 IMP by PCR 85498-4
3020503 NDM gene by PCR 73982-1
3020505 vanA/B by PCR 62261-3
3020650 Prosthetic Joint Infection Panel Summary 55112-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Prosthetic Joint Infection Panel by PCR