Ordering Recommendation

Recommended reflex panel to diagnose and subclassify suspected von Willebrand disease.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Transfer 3 mL platelet-poor plasma to an ARUP standard transport tube. (Min: 1.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum. Clotted. Nonfrozen or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 3 months

Methodology

Electrophoresis / Clotting / Microlatex Particle-Mediated Immunoassay / Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

1-3 days
If reflexed, add 4-11 days.

Reference Interval

Interpretive Data



Compliance Category

Modified FDA

Note

If von Willebrand factor (VWF) GPIbM activity or von Willebrand factor antigen (vWF Ag) or Factor VIII is low, von Willebrand Multimeric Analysis testing will be added.

Hotline History

N/A

CPT Codes

85240; 85246; 85397; if reflexed, add 85247

Components

Component Test Code* Component Chart Name LOINC
0030095 Factor VIII, Activity 3209-4
0030285 von Willebrand Factor, Antigen 27816-8
3019857 von Willebrand Factor, Activity (GPIbM) 107372-5
3020248 VWF:GPIbM / vWF Antigen Ratio 107641-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Coag
  • von Willebrand Profile
von Willebrand Factor Panel With Reflex to von Willebrand Multimers