3020127
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  FISH Interphase

FISH INT

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Time Sensitive

Ordering Recommendation

Use to order individual or multiple oncology FISH probes if standard FISH panels are not desired.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Nondiluted bone marrow aspirate collected in a heparinized syringe.
Also acceptable: Bone marrow or whole blood collected in green (sodium heparin).

Specimen Preparation

Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL) OR transport 5 mL whole blood (Min: 2 mL)

Storage/Transport Temperature

Preferred transport temp: Room temperature.

Unacceptable Conditions

Paraffin-embedded specimens. Clotted specimens.

Remarks

Desired FISH probe(s), specimen type, and pertinent clinical diagnosis are required with test order. Testing will not be performed until probe(s), specimen type, and diagnosis are provided; absence of this information will delay turnaround time.

Stability

Ambient: 2 days; Refrigerated: 2 days; Frozen: Unacceptable

Methodology

Fluorescence in situ Hybridization (FISH)

Performed

Sun-Sat

Reported

3-9 days

Reference Interval

By report

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note

Time required for testing can vary depending on specimen type and probes ordered.
Please indicate the names of probes needed for testing and specimen type. See Molecular Cytogenetics (FISH) Probe list in Additional Technical Information link.
Contact ARUP Genetics Service Support at extension 3301 to add a probe to a current specimen.
If more than one FISH probe is ordered, additional probe and analysis charges will be applied per probe.
Other specimen types may be acceptable, contact ARUP Genetics Support Services at extension 3301 for specific specimen collection and transportation instructions.
If chromosome analysis is not performed at ARUP on the same sample, Bone Marrow/PBL Culture Processing Fee (0093271) will be added to account for sample processing, and an additional charge will apply. If multiple FISH tests are ordered, 0093271 will only be applied to one of the FISH tests. If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
01/20/2026
X
N/A

CPT Codes

88271; 88275

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Components

Component Test Code* Component Chart Name LOINC
3020330 EER FISH Interphase 11526-1
3020331 FISH Interphase 57802-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • 21q22
  • RUNX1 Rearrangement
  • 3q27
  • 4q12
  • 5q Deletion (EGR1)/Monosomy 5
  • 5q32
  • 5q33.1
  • 7q Deletion(D7S486)/Mo
FISH Interphase